HPLC certified Agmatine Sulfate
What is Agmatine?
Agmatine is a byproduct of the amino acid arginine, but goes well beyond arginine in terms of benefits. Agmatine works through stimulating the release of pituitary hormones, including Luteinizing Hormone (LH) and Growth Hormone (GH). Agmatine has a variety of benefits, and can be beneficial and desirable for athletes and bodybuilders as well as fitness enthusiasts and people in search of a healthier lifestyle as they age. Agmatine also increases Nitric Oxide (N.O) through two pathways – by stimulating the release of Nitric Oxide, while also inhibiting types of Nitric Oxide Synthase (enzymes that break down N.O.)
What are the benefits of Agmatine?
Agmatine appears to be a very versatile supplement, we decided to carry it due to the overwhelming number of requests and the amount of information we found from postings all over the Internet. Peole using this supplement are reporting improved endurance, improved recovery, enhanced performance, dramatic and long lasting pumps, and improved overall body composition including increased lean muscle and decreased body-fat. Some people are reporting pumps that last all day with supplementation of 1-2 grams per day.
Specific Reported Benefits Include:
Increased Pumps – Although, we have contended that the creatine nitrates and amino acid nitrates help create the best pumps imaginable (and we still believe this to be the case) the effects of the nitrates tend to last up to 2-3 hours. People taking Agmatine sulfate have reported the pumps to be better than any of the conventional NO boosters, like Arginine AKG and Citrulline Malate and they also report the pumps lasting all day
Improved Insulin Response – Agmatine may help improve insulin response through enhanced insulin production, which can lead to positive benefits for those looking to improve body composition. Improved insulin response is thought of in bodybuilding circles as a key to a leaner, harder, more muscular body.
Nootropic Effect – Agmatine may help those looking to achieve a mental edge, whether it is in the gym or in day to day life. It can also help support a healthy mood and has anti-anxiety and antidepressant properties.
Stimulation of LH & GH Levels – In addition to the obvious appealing effect on overall body composition, the stimulation of GH and LH levels can also be beneficial for helping maintain a healthy lifestyle as we age. This stimulation of pituitary hormones may also lead to stimulation of other hormones such as IGF-1.
Neuroprotective Role – Agmatine plays a neuroprotective role due to its role as an antioxidant and its prevention of over excitation by glutamate.
Cardiovascular Benefits – Agmatine has a potential hypotensive benefit that may help aid in cardiovascular health. This hypotensive role is important in a healthy lifestyle for obvious reasons, but may also be found to be beneficial for bodybuilders or athletes.
Summary of Benefits:
Increased Nitric Oxide Syntheses
Inhibit NO Synthase (the enzyme responsible for NO breakdown)
Stimulation of L.H. (Luteinizing Hormone) & G.H. (Growth Hormone) Levels
Promote a Healthy & Positive Mood (Anti-Anxiety & Antidepressant Properties)
Promote Nutrient Delivery to Muscle Cells
Supports Overall Anabolic Environment
Enhanced Insulin Response
Potential Side Effects of Agmatine
Agmatine is derived from arginine, a primary amino acid. Agmatine acts as a neurotransmitter to induce production of growth hormone, nitric oxide, creatine and protein decrease blood glucose levels; and aid in the removal of nitrogen waste products from the body. A report in the Proceedings of the National Academy of Sciences indicates that agmatine is capable of preventing and treating spinal cord injuries, inflammation and neuropathy; however, every exogenous supplement has some side effects associated with use or overuse.
The patent for agmatine-containing products indicates that only three of the trial participants reported gastrointestinal disruptions at low doses. Those disruptions included diarrhea, nausea and vomiting that began after two days of taking agmatine and continued until treatment ceased. Only one of the people experiencing these problems dropped out of the clinical trial because of the discomfort caused by agmatine.
Lower Pain Threshold
A study published in the “European Journal of Pharmacology” indicated that large doses of agmatine actually lowered the overall pain threshold even though low doses improved overall response to chronic pain. Rats were utilized to determine if agmatine was capable of improving the response to acute pain from a new injury at low doses. Unfortunately, agmatine appears to have little ability to limit acute pain, even though the same dose appeared to stop pain perception from old injuries.
Agmatine is a low-affinity N-methyl-D-aspartate, or NMDA, antagonist; thus, the threat of neurotoxicity is possible although extremely unlikely. According to agmatine’s patent information, it has a 500,000-times lower affinity for NMDA receptors than typical antagonists. A report in “Science” indicates that NMDA antagonists may produce hallucinations, and they have been shown to cause morphological changes in the cerebral cortex of rats
Read more: http://www.livestrong.com/article/275087-agmatine-side-effects/#ixzz1QbRl78AK
Suggested Dosage of Agmatine
For most people, the usual agmatine dosage consists of 500mg twice daily. Some prefer to take 500mg pre workout, and then another 500mg dose after they finish their routine. Others take the entire dose at one time. Agmatine is readily available in a powder form, and the price varies according to manufacturer.
However, it is very important to note that there has not been very much literature published on Agmatine sulfate and recommended dosages have not been established.
Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Pregnant women should not take this supplement. Always consult your doctor first.
Shelf Life: This product will retain a 2 year shelf life from the date of manufacturer if properly sealed and stored in a dry, cool environment outside of direct sunlight.
Why Muscle Feast, LLC?
We guarantee our supplements to be the freshest and purest available: Muscle Feast, LLC supplements are manufactured under the strictest HACCP, FDA, and Kosher standards, producing the highest quality and purest supplements available. Our raw ingredients undergo state of the art analysis to ensure zero impurities and strict adherence to product labeling. Muscle Feast, LLC is registered with the FDA and is regulated and inspected regularly by the USDA under the direction of the State of Ohio Department of Agriculture. When it comes to price and quality you can’t beat Muscle Feast. We guarantee it!
Important facts you should know about our supplements:
Laboratory tested for purity
Strict adherence to GmP, HACCP and Kosher standards
Licensed and regularly inspected by The Ohio Department of Agriculture
Freshly manufactured – not expired or closeout
Backed by the Muscle Feast 30-day money back guarantee
How can our Quality be so high and our prices so low? We are able to keep our pricing so low because we are a relatively small manufacturer with very low overhead and we sell direct to the public. We source the same great suppliers used by more popular brands.
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